For Information, please, contact:

224 96 5917


Ph.D. position - information here



Institute of Pathological Physiology
U Nemocnice 5 , Praha 2, 128 53 mapa

DIČ: CZ00216208

IČ: 00216208

tel: +420 224 965 901

fax: +420 224 965 916

e-mail:                                                                                 Head: Assoc. Prof. Martin Vokurka, MD, PhD 



Welcome at the Institute of Pathological Physiology!


The Institute of Pathological Physiology is one of the teaching and research departments of the First Faculty of Medicine.


Our web pages include information for students and information about our research activities. We invite you to explore our Web site and encourage you to contact us with questions or comments.



  • Pathophysiology for 3rd year General medicine students
  • Pathophysiology for 2nd and 3rd year Dentistry students
  • Pathology and pathophysiology and Pathophysiology of nutrition for Bc. and MSc. programms of 1st Faculty of Mediciene, Charles University in Prague (only in Czech)
  • Postgraduate doctoral programe (PhD)

See more in section Study and Postgraduate study.



Basic and translational biomedical research to explore the etiology and pathogenesis of diseases is performed by several research groups of our department. We use cell biology, functional genomics and proteomics techniques to identify the mechanisms of cell, tissue, and organ defects. Research fields include experimental hematology and oncology (stem cells, transcription control, experimental therapy and diagnosis of malignancies, iron metabolism) , proteomics, mathematical modeling of nervous system.


See more in section Science and Research.




Tomáš Etrych, Lenka Daumová, Eva Pokorná, Diana Tušková, Ondřej Lidický, Věra Kolářová, Jan Pankrác, Luděk Šefc, Petr Chytil, Pavel Klener. Effective doxorubicin-based nano-therapeutics for simultaneous malignant lymphoma treatment and lymphoma growth imaging. Journal of controlled release. Submitted 2018. IF 7.877

GURIEVA I, et al. Erythropoietin administration increases splenic erythroferrone protein content and liver TMPRSS6 protein content in rats. Blood Cells Mol Dis. 2017 May;64:1-7. doi: 10.1016/j.bcmd.2017.02.007.


MASWABI BC, et al. Hematopoiesis in patients with mature B-cell malignancies is deregulated even in patients with undetectable bone marrow involvement. Haematologica. 2017 Apr;102(4):e152-e155. doi: 10.3324/haematol.2016.151571.



Other Publications